Binge-eating behavior and anorexia nervosa have shared and distinct genetic components – Nature Mental Health

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Genome-wide association studies of individuals with binge-eating behavior, anorexia nervosa or neither identify distinct genetic associations with each phenotype. Although both eating disorder phenotypes correlate genetically with other psychiatric conditions, binge eating also correlates with impulsivity, earlier age at first menstrual cycle and increased body mass, whereas anorexia nervosa shares genetics with metabolic traits.

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Fig. 1: Genetic correlations of eating phenotypes.

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References

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This is a summary of: Termorshuizen, J. D. et al. Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes. Nat. Ment. Health https://doi.org/10.1038/s44220-026-00698-2 (2026).

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Binge-eating behavior and anorexia nervosa have shared and distinct genetic components. Nat. Mental Health (2026). https://doi.org/10.1038/s44220-026-00697-3

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