psychosis
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agranulocytosis, antipsychotics, clozapine, Drugs, early intervention, FDA REMS, Finnish registry, first episode psychosis, negative symptoms, Psychiatry, psychosis, relapse prevention, schizophrenia, treatment-resistant schizophreniaEarly Clozapine in Schizophrenia: 34% Lower Relapse Risk
Clozapine has been the most effective antipsychotic in schizophrenia for almost 40…
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early psychosis, education and employment, first episode psychosis, functional recovery, individual placement and support, NEET, Psychiatry, Psychology, psychosis, psychosis recovery, schizophrenia, schizophrenia spectrum disorders, SEEearly trial, supported education, supported employment, therapy, vocational recoveryEarly Psychosis Vocational Recovery: 53.3% NEET in SEEearly Trial
A 2026 SEEearly baseline report found that 53.3% of 184 young people…
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autoimmune psychiatry, Brain, CSF biomarkers, immunopsychiatry, multiple sclerosis, neuroinflammation, neuroscience, OCD, Psychiatry, psychosis, sCD27, soluble CD27, T-cell activationsCD27 Biomarker Flags Autoimmune Disease in Severe Psychiatric Disorders
A 2026 immunopsychiatry cohort study found that soluble CD27 (sCD27), a marker…
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CBT, childhood trauma, delusions, EMDR, hallucinations, meta-analysis, prolonged exposure, psychological interventions, Psychological Medicine, psychosis, psychotherapy, systematic review, trauma, trauma-focused cognitive behavioural therapyTrauma-focused therapy for psychosis: helpful for delusions, less so for hallucinations
“The past is never dead. It’s not even past.” – William Faulkner…
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5-HT7, acute psychosis, antipsychotics, d2 receptor, Drugs, JEWEL trial, lurasidone, negative symptoms, Neurotransmitters, PANSS, positive symptoms, Psychiatry, psychosis, schizophreniaLurasidone Improves Positive Symptoms of Schizophrenia More Than Negative
Lurasidone is approved for schizophrenia and bipolar depression on the strength of…
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anhedonia, Black Americans, CBT for psychosis, defeatist beliefs, mediation analysis, microaggressions, negative symptoms, PANSS, Psychiatry, Psychology, psychosis, racial discrimination, racial stress, schizophrenia, therapyBlack Americans Diagnosed with Schizophrenia 2.42x the Rate of White Americans: More Negative Symptoms
Black Americans are diagnosed with schizophrenia-spectrum disorders at 2.42 times the rate…
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anti-ribosomal P, antiphospholipid antibodies, autoimmune, complement, first episode psychosis, lupus, neuropsychiatric lupus, NPSLE, Psychiatry, psychosis, schizophrenia, SLELupus Psychosis: 4.5% Prevalence and Antibody Predictors
Research Highlights Across 65 studies and 31,495 lupus patients, 4.5% develop psychosis…
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antipsychotics, British Journal of Psychiatry, cardiometabolic risk, causal inference, comorbidities, comorbidity, early intervention, Editor Eimear Foley, first episode psychosis, haloperidol, mediation analysis, metabolic health, mortality gap, obesity, olanzapine, personalised medicine, physical health inequalities, precision psychiatry, prediction modelling, psychosis, randomised controlled trial, schizophrenia, side effects, topical, weight gainCan we predict and prevent weight gain in early psychosis?
On average, people with psychosis die 15 years earlier than the general…
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#UCLJournalClub, antipsychotic discontinuation, antipsychotics, dose reduction, Editor Dafni Katsampa, first episode psychosis, JAMA Psychiatry, NICE guidelines, psychosis, randomised controlled trial, schizophrenia, secondary care, topical, UCL Division of PsychiatryStop, reduce or stay on antipsychotics after first-episode psychosis?
Recovery from first-episode psychosis (FEP) often brings a sense of relief, but…
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bipolar disorder, Diagnosis, digital health, digital innovation, digital mental health, early intervention, Editor Simon Bradstreet, Lancet Psychiatry, natural language processing, prediction, prediction model, psychosis, risk factors, routinely collected data, schizophreniaSpotting bipolar and psychosis risk earlier using routine clinical records
The signs of mental health conditions, such as schizophrenia and bipolar disorder,…
