Mapping the human brain histamine system at the molecular, structural and functional levels – Nature Mental Health

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Nature Mental Health volume 4pages 694–695 (2026) Cite this article

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This study presents a multimodal, systems-level map of the human brain histamine system, integrating transcriptomics, molecular imaging, developmental trajectories and cognitive meta-analysis. The findings link histaminergic system architecture to higher-order cognition and vulnerability to major psychiatric disorders.

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Fig. 1: Multimodal spatial organization of the human brain histaminergic system.

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References

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This is a summary of: Martins, D. et al. Mapping histamine pathway networks in the human brain across cognition and psychiatric disorders. Nat. Mental Health https://doi.org/10.1038/s44220-026-00637-1 (2026).

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Mapping the human brain histamine system at the molecular, structural and functional levels. Nat. Mental Health 4, 694–695 (2026). https://doi.org/10.1038/s44220-026-00641-5

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