Alzheimer’s disease
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alpha-synuclein, Alzheimer’s disease, blood brain barrier, Brain, microplastics, Neurodegenerative Diseases, neuroinflammation, neuroscience, oxidative stress, parkinson’s diseaseMicroplastics and Parkinson’s Disease: 6 Plausible Brain-Risk Pathways
A 2026 mechanistic review linked microplastics to 6 proposed Alzheimer’s disease pathways…
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Alzheimer’s disease, amyloid beta, blood brain barrier, Brain, cerebral blood flow, dementia biomarkers, Neurodegenerative Diseases, neuroscience, neurovascular unit, pericytesAlzheimer’s Neurovascular Unit Dysfunction May Start Before Amyloid
A 2026 review argues that neurovascular-unit dysfunction may precede amyloid-beta generation in…
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A4 study, ADNI, Alzheimer’s disease, amyloid PET, blood biomarker, Brain, calibration, cognition, machine learning, negative predictive value, Neurodegenerative Diseases, p-tau217, plasma biomarkersAlzheimer’s Blood Biomarker Models Lose Rule-Out Power Across Cohorts
A 2026 ADNI/A4 validation study found that Alzheimer’s plasma-biomarker machine-learning models still…
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A-beta 42/40, Alzheimer’s disease, amyloid PET, blood biomarkers, Brain, Clarity AD, cognition, GFAP, lecanemab, maintenance dosing, Neurodegenerative Diseases, p-tau181, PK/PD modelingLecanemab Blood Biomarkers Rebound Faster Than Amyloid PET After Stopping
Lecanemab blood biomarkers may rebound much faster than amyloid PET after treatment…
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alpha-synuclein co-pathology, alpha-synuclein SAA, ALZAN cohort, Alzheimer’s disease, Brain, CSF biomarkers, lewy body dementia, memory clinic biomarkers, Neurodegenerative Diseases, neuroscience, RT-QuICAlpha-Synuclein SAA Detected 95% of Lewy Body Dementia in ALZAN
A 2026 ALZAN memory-clinic cohort found that cerebrospinal-fluid alpha-synuclein seed amplification assay…
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Alzheimer’s disease, amygdala, blood biomarkers, Brain, cognition, cognitive impairment, dementia biomarkers, hippocampus, MRI radiomics, Neurodegenerative Diseases, neuroscience, olfactory dysfunction, pTau217Olfactory MRI Radiomics Link pTau217 to Alzheimer’s Cognition
A 2026 multi-cohort Alzheimer’s disease study found that MRI radiomics from the…
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Alzheimer’s disease, Brain, chromatin remodeling, iPSC neurons, Lamin B receptor, Lamin B2, Neurodegenerative Diseases, neuroscience, nuclear lamina, PS19 mice, pTau217, tau oligomers, tauopathyTau Oligomers Disrupted Nuclear Lamina in Alzheimer’s Disease Models
A 2026 Acta Neuropathologica study found that oligomeric tau was linked to…
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Alzheimer’s disease, amyloid beta, autophagy, genetics, lysosomes, mouse models, NDST3, Neurodegenerative Diseases, neuroscience, tau pathology, V-ATPaseNDST3 Suppression Restores Lysosome Acidity in Alzheimer’s Mouse Models
A 2026 mechanistic Alzheimer’s study found that suppressing NDST3 shifted lysosomal pH…
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ADNI, Alzheimer’s disease, ANA-GNN, artificial-intelligence, Brain, clinical decision support, cognition, dementia diagnosis, graph neural network, hippocampus, machine learning, mild cognitive impairment, Neurodegenerative Diseases, neuroimaging, neuroscience, posterior cingulate cortex, structural MRIAlzheimer’s AI MRI Diagnosis: ANA-GNN Reaches 85.23% Accuracy in ADNI
A 2026 ADNI study reported 85.23% accuracy for ANA-GNN, a graph neural…
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Alzheimer’s disease, amyloid beta, Brain, CD8 T cells, cerebral amyloid angiopathy, CXCL10, CXCR3, microglia, Neurodegenerative Diseases, neuroinflammation, neuroscience, spatial transcriptomics, type I interferonAlzheimer’s Amyloid Plaques Recruit CD8 T Cells Through Type I Interferon
A 2026 single-cell and spatial-transcriptomics study of 21,156 brain immune cells found…
