Alzheimer’s disease
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AIP4, Alzheimer’s disease, amyloid beta, APP PS1 mice, Brain, cell cycle re-entry, clomipramine, drug repurposing, Drugs, Itch, memory, Neurodegenerative Diseases, neuronal apoptosisClomipramine Improved Alzheimer’s Mouse Memory by Blocking Itch in 45 Days
A 2026 iScience study found that 45 days of clomipramine improved spatial,…
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AD/ADRD, Alzheimer’s disease, APOE-e4, Brain, cardiovascular risk, cognitive decline, Dementia, Drugs, Kaiser Permanente, LDL cholesterol, Neurodegenerative Diseases, observational bias, statins, target trial emulationStatins and Dementia Risk: No Long-Term Signal in 322,358 Patients
Statins do not look like a dementia-prevention drug, but they do not…
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ADNI, Alzheimer’s disease, amyloid, APOE, APOE-e4, blood biomarker, Brain, cognition, donanemab, Drugs, genetics, lecanemab, longitudinal cohort, mild cognitive impairment, Neurodegenerative Diseases, neuroscience, p-tau217, preclinical ADPlasma p-tau217 Blood Test Predicts Alzheimer’s Risk 1.5x Stronger in APOE-e4
Until recently, Alzheimer’s pathology could only be confirmed in living patients via…
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Alzheimer’s disease, Anxiety, cognition, Dementia, depression, loneliness, meta-analysis, Neurodegenerative Diseases, older adults, social isolation, suicideHow Much Does Loneliness Raise Dementia and Suicide Risk?
Research Highlights Loneliness is associated with substantially elevated risk of both Alzheimer’s…
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ageing, Alzheimer’s disease, Biological Psychiatry, causality, CHARLS, chronotype, circadian rhythm, cognition, cognitive ageing, cognitive decline, cohort study, Dementia, Editor Eimear Foley, insomnia, mild cognitive impairment, modifiable risk factors, napping, neurodegenerative disease, older adult, sleep, sleep disorders, sleep disturbance, sleep hygiene, sleep problems, sleep quality, UK BiobankChanging sleep patterns linked to cognitive decline and dementia
Sleep is essential for both physical and mental health. Not getting the…
