amyloid beta
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Alzheimer’s disease, amyloid beta, blood brain barrier, Brain, cerebral blood flow, dementia biomarkers, Neurodegenerative Diseases, neuroscience, neurovascular unit, pericytesAlzheimer’s Neurovascular Unit Dysfunction May Start Before Amyloid
A 2026 review argues that neurovascular-unit dysfunction may precede amyloid-beta generation in…
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Alzheimer’s disease, amyloid beta, autophagy, genetics, lysosomes, mouse models, NDST3, Neurodegenerative Diseases, neuroscience, tau pathology, V-ATPaseNDST3 Suppression Restores Lysosome Acidity in Alzheimer’s Mouse Models
A 2026 mechanistic Alzheimer’s study found that suppressing NDST3 shifted lysosomal pH…
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Alzheimer’s disease, amyloid beta, Brain, CD8 T cells, cerebral amyloid angiopathy, CXCL10, CXCR3, microglia, Neurodegenerative Diseases, neuroinflammation, neuroscience, spatial transcriptomics, type I interferonAlzheimer’s Amyloid Plaques Recruit CD8 T Cells Through Type I Interferon
A 2026 single-cell and spatial-transcriptomics study of 21,156 brain immune cells found…
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AIP4, Alzheimer’s disease, amyloid beta, APP PS1 mice, Brain, cell cycle re-entry, clomipramine, drug repurposing, Drugs, Itch, memory, Neurodegenerative Diseases, neuronal apoptosisClomipramine Improved Alzheimer’s Mouse Memory by Blocking Itch in 45 Days
A 2026 iScience study found that 45 days of clomipramine improved spatial,…
