genetics
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autophagy, genetics, lysosomes, mitochondria, mitophagy, Neurodegenerative Diseases, neuroscience, Parkin, parkinson’s disease, PINK1, ubiquitinPINK1 and Parkin Link Parkinson’s Disease to Failed Mitochondrial Cleanup
A 2026 review ties the Parkinson’s disease genes PINK1 and parkin to…
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cognitive impairment, depression, depression genetics, endothelial dysfunction, first-episode depression, genetics, geriatric depression, inflammatory markers, MMSE, neuroscience, nitric oxide synthase, NOS3, Psychiatry, rs1799983NOS3 TT Variant Linked to 1.72x Cognitive Risk in First-Episode Depression
A 2026 cross-sectional study of 519 older adults with first-episode depression found…
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autophagy, genetics, lysosomes, neurodegeneration, Neurodegenerative Diseases, neuroscience, parkinson’s disease, potassium channel, proton channel, TMEM175TMEM175 Proton Channel Finding Clarifies Parkinson’s Lysosome Risk
A 2026 PNAS study found that TMEM175 behaves as a pH-sensitive lysosomal…
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behavior genetics, Cantril ladder, gene-environment correlation, genetics, happiness setpoint, heritability, life events, longitudinal study, Oslo Twin Project, Psychiatry, Psychology, subjective wellbeing, teen wellbeing, twin studyTeen Wellbeing: Genes Explain 81% Stability, Life Events 1% Change
People expect life events to drive adolescent wellbeing — conflicts and breakups…
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atypical absence seizures, Autism, autistic behaviors, caregiver report, developmental epileptic encephalopathy, epilepsy, genetics, medRxiv preprint, seizure semiology, SYNGAP1SYNGAP1 Autistic Behaviors Linked to Seizure Type, Not Frequency
A 337-person SYNGAP1-DEE registry preprint found caregiver-reported autistic behavior scores linked most…
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Brain, brain genetics, cerebral small vessel disease, genetics, lacunar stroke, medRxiv preprint, Mendelian randomization, neuroscience, postprandial glucose, type 2 diabetesPost-Meal Glucose Genetics Linked to Lacunar Stroke Risk
A 2026 medRxiv genetic analysis linked type 2 diabetes and 2-hour postprandial…
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ABCD study, Autism, Brain, brain microstructure, genetic correlation, genetics, ICVF, iPSYCH, Mendelian randomization, neurite density, neuroscience, NODDI, PGS, polygenic scores, UK BiobankAutism Polygenic Scores Linked to Lower Neurite Density
A 2025 paper by Gu et al. in Molecular Psychiatry — the…
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complement C4, crispr, CYFIP1, genetics, gwas, IRF8, ITGB2, microglia, MSR1, neuroscience, Psychiatry, schizophrenia, SYK, synaptic pruning, TREM2Schizophrenia Risk Genes Reshape Microglial Pruning in CRISPR Screen
Schizophrenia’s genetic architecture sits awkwardly between neurons and the immune system. A…
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depression, Diet & Nutrition, genetics, iq, late diagnosis, metabolic control, newborn screening, phenylalanine, phenylketonuria, PKU children, Psychiatry, quality of life, suicidal thoughtsLate-Diagnosed PKU Linked to Depression in Children
A 2026 Egyptian study of 76 children found a sharp mental-health gradient…
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clinical staging, depression, early mental illness, genetics, gray matter volume, neuroscience, polygenic risk score, PRONIA, psychiatric biomarkers, Psychiatry, Psychology, psychosis risk, recent-onset depression, recent-onset psychosis, schizophrenia, transdiagnostic severityEarly Mental Illness Severity Tracks Genetics and Brain Volume in PRONIA
A 2026 PRONIA preprint involving 727 discovery-sample participants found that early mental…
