antidepressants
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adverse effects, antidepressants, depression, depression treatment, Drugs, global mental health, low- and middle-income countries, Pakistan, pharmacovigilance, prescribing patterns, Psychiatry, Psychology, side effects, ssris, tricyclicsAntidepressant Use in Pakistan (2026): SSRI Prescribing Patterns and Patient-Reported Side Effects
Most antidepressant pharmacovigilance data come from high-income countries, leaving prescribing patterns and…
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anhedonia, antidepressants, Brain, cross-over RCT, depression, dopamine, locus coeruleus, major depressive disorder, motivation, neuroscience, Neurostimulation, Neurotransmitters, Psychiatry, reward-effort, treatment-resistant depression, tVNS, vagus nerve stimulationtVNS Alters Effort and Reward Decisions in Severe Depression
An ear-clip that modulates mood by stimulating the vagus nerve has obvious…
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antidepressants, depression, Drugs, FDA rejection, functional unblinding, Lykos, mdma, media coverage, neuroscience, psilocybin, psychedelic medicine, Psychiatry, Psychology, PTSD, science communication, Stress, treatment-resistant depressionPsychedelic Media Coverage Outpaced Evidence (2017–2024)
Psychedelic-assisted therapy has been one of the most-covered mental-health stories of the…
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AMPA receptor, antidepressants, Brain, chronic mild stress, comorbidity, depression, Drugs, GluA1, glutamate, ketamine, neuroscience, Neurotransmitters, PTSD, rat model, single prolonged stress, Stress, synaptic plasticityPTSD With Depression Hits AMPA Receptors Harder in Rat Models
PTSD and major depressive disorder co-occur in roughly half of patients with…
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anticoagulants, antidepressants, Anxiety, atrial fibrillation, bleeding, case-crossover, cohort study, depression, DOACs, drug interactions, Drugs, gastrointestinal bleeding, Interactions, intracranial hemorrhage, ssrisSSRIs + DOACs: No Excess Bleeding vs. Other Antidepressants
SSRIs raise bleeding risk on their own. DOACs (direct oral anticoagulants —…
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adverse events, antidepressants, British Journal of Psychiatry, clinical trial, depression, difficult-to-treat depression, Editor Eimear Foley, feasibility, major depressive disorder, mdma, MDMA-assisted psychotherapy, open label study, placebo, proof-of-principle, psychedelics, psychotherapy, randomised controlled trial, remission, Safety, Suicidal Ideation, tolerability, topicalMDMA-assisted therapy for depression: a promising but early first step
MDMA was first made in 1912 as an accidental byproduct of a…
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aerobic exercise, antidepressants, Anxiety, bdnf, depression, exercise, meta-analysis, Natural Cures, resistance trainingExercise for Depression and Anxiety: What the Evidence Says
Research Highlights Exercise works. Across the strongest available meta-analyses, regular exercise produces…
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antidepressants, Bayesian analysis, clinical trials, depression, difficult-to-treat, Editor Eimear Foley, frequentist analysis, JAMA Psychiatry, meta-analysis, non-randomised trials, placebo effect, psilocybin, psychedelic-assisted therapy, psychedelics, systematic review, topical, unblindingIn the Land of the Unblind: are psychedelics really better than antidepressants?
Around 30% of people don’t respond to traditional antidepressants (TADs), such as…
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antidepressants, cohort study, depression, difficult-to-treat, Editor Eimear Foley, electroconvulsive therapy, health inequalities, maternal depression, Nature Mental Health, perinatal depression, perinatal mental health, personalised care, postpartum depression, pregnancy, register-based study, risk factors, Sweden, Swedish cohort study, Transcranial Magnetic Stimulation, treatment resistance, women’s healthWhen the treatment doesn’t work: what predicts difficult-to-treat postpartum depression?
Giving birth to a baby is undoubtedly a major event in a…
