major depressive disorder
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behavioral activation, cognitive behavioral therapy, depression, depression remission, exercise priming, major depressive disorder, pilot randomized trial, Psychology, therapeutic alliance, therapyExercise Before CBT Raised Depression Remission to 69% in Pilot Trial
A 40-person pilot trial found depression remission in 69% of adults who…
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Brain, cardiolipins, depression, gut microbiome, IL-6, inflammation, major depressive disorder, Morganella morganii, neuroscience, phospholipids, TLR1, TLR2Morganella Phospholipids Triggered IL-6 in Depression Mechanism Study
A 2025 Journal of the American Chemical Society study identified 4 unusual…
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actigraphy, CAN-BIND Wellness Monitoring, Chronotherapy, circadian rhythms, cohort study, depression, digital biomarkers, digital health, digital innovation, digital mental health, Editor Eimear Foley, JAMA Psychiatry, longitudinal study, major depressive disorder, monitoring, Montgomery-Åsberg Depression Rating Scale, recurrence, relapse, relapse prevention, remission, rest-activity rhythms, sleep, sleep disorders, sleep disturbance, sleep hygiene, topical, wearable technologySleep and rest-activity rhythms in depression relapse: can wearables see the storm coming?
You have begun to emerge from the fog that had settled over…
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depression, HDRS, heat-shock proteins, IL-6, inflammation, major depressive disorder, Natural Cures, neuroscience, Psychiatry, RNA-seq, whole-body hyperthermiaWhole-Body Hyperthermia for Depression: IL-6 Heat Genes
Whole-body hyperthermia looks less like generic relaxation and more like a timed…
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antidepressants, cyp2c19, depression, DIVERGE, genetics, major depressive disorder, Pakistan, pharmacogenetics, polypharmacy, Psychiatry, psychotherapy access, social support, treatment-resistant depressionTreatment-Resistant Depression in Pakistan: 34% TRD, 86% Polypharmacy
A 2026 DIVERGE analysis of 3,677 antidepressant-exposed patients with major depressive disorder…
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anhedonia, anti-inflammatory, Anxiety, C-reactive protein, cytokines, depression, Editor Nina Higson-Sweeney, fatigue, inflammation, interleukin 6, JAMA Psychiatry, major depressive disorder, proof-of-concept, quality of life, randomised controlled trial, somatic symptoms, tocilizumab, topicalTargeting inflammation in depression: a proof-of-concept worth following
Back in the days when we were all cave-dwelling hunters and gatherers,…
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Brain, cognitive remediation, depression, gamma neuromodulation, GENUS, iTBS, major depressive disorder, meta-analysis, Neurostimulation, schizophrenia, tACS, therapy, theta-burst stimulation, TMS, Tsai labGamma Brain Stimulation Helps Schizophrenia More Than Depression
A 2026 meta-analysis of 56 controlled trials found the clearest gamma-frequency neuromodulation…
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bipolar disorder, cognition, cognitive development, cognitive function, depression, high-risk children, major depressive disorder, meta-analysis, offspring cognition, parental mental illness, schizophreniaParental Mental Illness vs. Offspring Cognition: Schizophrenia, Bipolar, Depression
Research Highlights The “kids of mentally ill parents do worse” idea flattens…
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depression, dysbiosis, female, gut bacteria, gut brain axis, gut microbiome, major depression, major depressive disorder, male, mdd, sex differencesSex Differences of Gut Bacteria (Microbiome) in Major Depression (2024 Review)
The intricate relationship between the gut microbiome and major depressive disorder (MDD)…
