major depressive disorder
-
anhedonia, anti-inflammatory, Anxiety, C-reactive protein, cytokines, depression, Editor Nina Higson-Sweeney, fatigue, inflammation, interleukin 6, JAMA Psychiatry, major depressive disorder, proof-of-concept, quality of life, randomised controlled trial, somatic symptoms, tocilizumab, topicalTargeting inflammation in depression: a proof-of-concept worth following
Back in the days when we were all cave-dwelling hunters and gatherers,…
-
Brain, cognitive remediation, depression, gamma neuromodulation, GENUS, iTBS, major depressive disorder, meta-analysis, Neurostimulation, schizophrenia, tACS, therapy, theta-burst stimulation, TMS, Tsai labGamma Brain Stimulation Helps Schizophrenia More Than Depression
A 2026 meta-analysis of 56 controlled trials found the clearest gamma-frequency neuromodulation…
-
anhedonia, antidepressants, Brain, cross-over RCT, depression, dopamine, locus coeruleus, major depressive disorder, motivation, neuroscience, Neurostimulation, Neurotransmitters, Psychiatry, reward-effort, treatment-resistant depression, tVNS, vagus nerve stimulationtVNS Alters Effort and Reward Decisions in Severe Depression
An ear-clip that modulates mood by stimulating the vagus nerve has obvious…
-
adverse events, antidepressants, British Journal of Psychiatry, clinical trial, depression, difficult-to-treat depression, Editor Eimear Foley, feasibility, major depressive disorder, mdma, MDMA-assisted psychotherapy, open label study, placebo, proof-of-principle, psychedelics, psychotherapy, randomised controlled trial, remission, Safety, Suicidal Ideation, tolerability, topicalMDMA-assisted therapy for depression: a promising but early first step
MDMA was first made in 1912 as an accidental byproduct of a…
-
bipolar disorder, cognition, cognitive development, cognitive function, depression, high-risk children, major depressive disorder, meta-analysis, offspring cognition, parental mental illness, schizophreniaParental Mental Illness vs. Offspring Cognition: Schizophrenia, Bipolar, Depression
Research Highlights The “kids of mentally ill parents do worse” idea flattens…
-
depression, dysbiosis, female, gut bacteria, gut brain axis, gut microbiome, major depression, major depressive disorder, male, mdd, sex differencesSex Differences of Gut Bacteria (Microbiome) in Major Depression (2024 Review)
The intricate relationship between the gut microbiome and major depressive disorder (MDD)…
-
depression, genes, genetics, major depression, major depressive disorder, mdd, mendellian randomization, obstructive sleep apnea, osa, psychiatric disorders, sleep, sleep apneaGenetics of Major Depression Linked to Increased Risk of Obstructive Sleep Apnea (OSA) (2024 Study)
In a new study leveraging Mendelian Randomization, researchers highlight the complex interplay…
