Psychiatry
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anhedonia, antidepressants, Brain, cross-over RCT, depression, dopamine, locus coeruleus, major depressive disorder, motivation, neuroscience, Neurostimulation, Neurotransmitters, Psychiatry, reward-effort, treatment-resistant depression, tVNS, vagus nerve stimulationtVNS Alters Effort and Reward Decisions in Severe Depression
An ear-clip that modulates mood by stimulating the vagus nerve has obvious…
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Anxiety, benzodiazepines, depression, Drugs, Iceland, older adults, psychiatric epidemiology, Psychiatry, Psychology, psychotropic prescribing, public-health, registry data, sleep, sleep disordersIceland Psychiatric Data: 21% Diagnosed, 34% on Psychotropics (2026)
Iceland is a registry-rich country with a small enough population that genuinely…
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antipsychotics, cardiovascular risk, case-control study, cognition, Dementia, Diabetes, Drugs, head injury, integrated care, metabolic syndrome, modifiable risk factors, Neurodegenerative Diseases, Psychiatry, Psychology, psychosis, schizophrenia, smokingSchizophrenia Dementia Risk: Diabetes, Head Injury, Substance Use
Patients with schizophrenia have substantially elevated dementia risk compared to the general…
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ADHD, Autism, autism spectrum disorder, comorbidity, depression, diagnostic overshadowing, epidemiology, intellectual disability, NHIS, pediatric psychiatry, Psychiatry, Psychology, South Korea, time trendsIntellectual Disability in Korean Children and Psychiatric Disorders (ADHD 42%, Depression 19%)
Children with intellectual disability are 3–4x more likely to have a comorbid…
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antipsychotics, AUROC, clinical decision support, clozapine, Drugs, electronic health records, InterSePT, machine learning, natural language processing, Psychiatry, psychosis, schizophrenia, treatment-resistant schizophrenia, xgboostMachine Learning Predicts Clozapine Initiation in Schizophrenia
Clozapine is the only medication with proven efficacy for treatment-resistant schizophrenia, yet…
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assisted dying, base rate problem, epidemiology, euthanasia, mental health policy, Netherlands, psychiatric ethics, Psychiatry, Psychology, suicide, suicide-prevention, Werther effect, youth mental healthYouth Psychiatric Euthanasia in the Netherlands (Dutch Suicide Data)
The Netherlands has practiced euthanasia for mental suffering since the early 2000s,…
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5-HT7, acute psychosis, antipsychotics, d2 receptor, Drugs, JEWEL trial, lurasidone, negative symptoms, Neurotransmitters, PANSS, positive symptoms, Psychiatry, psychosis, schizophreniaLurasidone Improves Positive Symptoms of Schizophrenia More Than Negative
Lurasidone is approved for schizophrenia and bipolar depression on the strength of…
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antidepressants, depression, Drugs, FDA rejection, functional unblinding, Lykos, mdma, media coverage, neuroscience, psilocybin, psychedelic medicine, Psychiatry, Psychology, PTSD, science communication, Stress, treatment-resistant depressionPsychedelic Media Coverage Outpaced Evidence (2017–2024)
Psychedelic-assisted therapy has been one of the most-covered mental-health stories of the…
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ABCD study, addiction, adolescent, Cannabis, cbd, cognition, cognitive trajectory, Drugs, hair toxicology, longitudinal cohort, marijuana, neurocognition, Prevention, Psychiatry, Psychology, thcTeenage Cannabis Use vs. Cognition and Brain Development: THC vs. CBD (Toxicology Data)
Studies of adolescent cannabis effects on cognition have been limited by self-report…
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binge eating disorder, Brain, bupropion, contrave, dopamine, Drugs, eating disorders, food reward, human laboratory, lisdexamfetamine, mu-opioid receptor, naltrexone, neuroscience, Neurotransmitters, obesity, POMC neurons, Psychiatry, PsychologyNaltrexone/Bupropion Reduced Food Intake in Binge-Eating Lab Study
Lisdexamfetamine remains the only FDA-approved medication for binge-eating disorder — a serious…
