Psychiatry
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complement C4, crispr, CYFIP1, genetics, gwas, IRF8, ITGB2, microglia, MSR1, neuroscience, Psychiatry, schizophrenia, SYK, synaptic pruning, TREM2Schizophrenia Risk Genes Reshape Microglial Pruning in CRISPR Screen
Schizophrenia’s genetic architecture sits awkwardly between neurons and the immune system. A…
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ALS anxiety, amyotrophic lateral sclerosis, Anxiety, Beck Depression Inventory, depression, frontotemporal dementia, motor neuron disease, Neurodegenerative Diseases, Psychiatry, psychological distress, STAI, state anxiety, trait anxietyALS Anxiety: 18% State, 14% Trait in 433 Patients
In 433 non-demented amyotrophic lateral sclerosis (ALS) patients, clinically significant anxiety was…
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Anxiety, APRIL, biomarkers, Cancer Disparities Research Network, chronic inflammation, gp130, health disparities, IL-6, mind-body, MMP-1, Psychiatry, Psychology, Stress, underserved populationsAnxiety Biomarkers: gp130, MMP-1, APRIL in 190 Adults
The link between psychological stress and chronic inflammation is well-documented — what’s…
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depression, HDRS, heat-shock proteins, IL-6, inflammation, major depressive disorder, Natural Cures, neuroscience, Psychiatry, RNA-seq, whole-body hyperthermiaWhole-Body Hyperthermia for Depression: IL-6 Heat Genes
Whole-body hyperthermia looks less like generic relaxation and more like a timed…
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AI chatbots, AI companionship, AI therapy, Character.ai, GPT-4o, language models, medical advice, MedQA, mental health apps, Psychiatry, Psychology, sycophancy, TruthfulQA, warmth fine-tuningWarm AI Chatbots Made More Errors and Affirmed False Beliefs
Warm AI chatbots can feel more supportive while becoming less reliable. In…
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agranulocytosis, antipsychotics, clozapine, Drugs, early intervention, FDA REMS, Finnish registry, first episode psychosis, negative symptoms, Psychiatry, psychosis, relapse prevention, schizophrenia, treatment-resistant schizophreniaEarly Clozapine in Schizophrenia: 34% Lower Relapse Risk
Clozapine has been the most effective antipsychotic in schizophrenia for almost 40…



