schizophrenia
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antipsychotics, cardiometabolic health, cardiovascular disease, cardiovascular screening, clinical prediction model, cohort study, early intervention in psychosis, Editor Eimear Foley, metabolic syndrome, mixed methods, mortality gap, obesity, personalised care, precision psychiatry, prediction, preventive healthcare, psychosis, risk factors, risk prediction, schizophrenia, severe mental illness, shared decision making, The Lancet Psychiatry, type 2 diabetes, weight gainPsychosis and metabolic risk: PsyMetRiC 2.0 reaches the clinic
Compared to the general population, individuals with psychosis have a 15-year reduced…
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Brain, brain imaging biomarkers, cerebral perfusion, independent component analysis, NeuroMark, neuroscience, Psychiatry, resting cerebral blood flow, schizophrenia, spatially constrained ICA, spectNeuroMark SPECT Found 23 Schizophrenia Perfusion Network Changes
A 2026 medRxiv preprint built a reusable NeuroMark SPECT template from 2…
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Autism, Brain, cortical folding, developing Human Connectome Project, functional connectivity, gyri, neonatal brain development, neonatal MRI, neurodevelopment, neuroscience, schizophrenia, structural connectivity, structure-function coupling, sulciNeonatal Brain MRI Shows Gyri Are Connectivity Hubs by 38-44 Weeks
A 2026 developing Human Connectome Project analysis of 438 full-term neonates found…
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anhedonia, bipolar disorder, Brain, endophenotype, fMRI, monetary incentive delay task, negative symptoms, neuroscience, polygenic risk score, Psychiatry, psychosis, reward processing, schizophrenia, ventral striatumReward Activation Failed as Bipolar-Psychosis Endophenotype
A 244-person functional MRI study found no significant evidence that ventral striatum…
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cognition, cognitive remediation, Corsi block-tapping, dlpfc, Forward Digit Span, Neurostimulation, non invasive brain stimulation, Psychiatry, schizophrenia, sham-controlled trial, tdcs, transcranial direct current stimulation, working memorySingle-Session tDCS Fails Working-Memory Test in Schizophrenia
Transcranial direct current stimulation (tDCS) has been pitched as a scalable cognitive-enhancement…
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complement C4, crispr, CYFIP1, genetics, gwas, IRF8, ITGB2, microglia, MSR1, neuroscience, Psychiatry, schizophrenia, SYK, synaptic pruning, TREM2Schizophrenia Risk Genes Reshape Microglial Pruning in CRISPR Screen
Schizophrenia’s genetic architecture sits awkwardly between neurons and the immune system. A…
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agranulocytosis, antipsychotics, clozapine, Drugs, early intervention, FDA REMS, Finnish registry, first episode psychosis, negative symptoms, Psychiatry, psychosis, relapse prevention, schizophrenia, treatment-resistant schizophreniaEarly Clozapine in Schizophrenia: 34% Lower Relapse Risk
Clozapine has been the most effective antipsychotic in schizophrenia for almost 40…
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amygdala, bipolar disorder, depression, functional connectivity, hippocampus, major depression, neuroscience, Psychiatry, Psychology, resting-state fMRI, schizophrenia, striatum, subcortical connectivity, thalamusSubcortical Connectivity Differs in Schizophrenia, Bipolar, Depression
A 2026 resting-state fMRI study of 800 adults found intra-thalamic hypoconnectivity across…
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clinical staging, depression, early mental illness, genetics, gray matter volume, neuroscience, polygenic risk score, PRONIA, psychiatric biomarkers, Psychiatry, Psychology, psychosis risk, recent-onset depression, recent-onset psychosis, schizophrenia, transdiagnostic severityEarly Mental Illness Severity Tracks Genetics and Brain Volume in PRONIA
A 2026 PRONIA preprint involving 727 discovery-sample participants found that early mental…
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early psychosis, education and employment, first episode psychosis, functional recovery, individual placement and support, NEET, Psychiatry, Psychology, psychosis, psychosis recovery, schizophrenia, schizophrenia spectrum disorders, SEEearly trial, supported education, supported employment, therapy, vocational recoveryEarly Psychosis Vocational Recovery: 53.3% NEET in SEEearly Trial
A 2026 SEEearly baseline report found that 53.3% of 184 young people…
