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Brain, cholinergic, cognition, cognitive fluctuations, Diagnosis, DLB, donepezil, lewy body dementia, Mayo Fluctuations Composite, Neurodegenerative Diseases, neuroleptic sensitivity, neuroscience, Parkinson’s dementia, REM sleep behavior disorder, rivastigmine, sleepLewy Body Dementia Cognitive Fluctuations Affect 75-90% of Patients
Cognitive fluctuations are a defining feature of dementia with Lewy bodies (DLB),…
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assisted dying, base rate problem, epidemiology, euthanasia, mental health policy, Netherlands, psychiatric ethics, Psychiatry, Psychology, suicide, suicide-prevention, Werther effect, youth mental healthYouth Psychiatric Euthanasia in the Netherlands (Dutch Suicide Data)
The Netherlands has practiced euthanasia for mental suffering since the early 2000s,…
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5-HT7, acute psychosis, antipsychotics, d2 receptor, Drugs, JEWEL trial, lurasidone, negative symptoms, Neurotransmitters, PANSS, positive symptoms, Psychiatry, psychosis, schizophreniaLurasidone Improves Positive Symptoms of Schizophrenia More Than Negative
Lurasidone is approved for schizophrenia and bipolar depression on the strength of…
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Anxiety, depression, indirect trauma, media exposure, media literacy, Psychiatry, psychological effects, Psychology, PTSD, Social media, Stress, therapy, uncensored media, vicarious traumatization, war traumaUncensored Media Trauma and Modern Psychological Effects
The internet era has dramatically changed how people are exposed to traumatic…
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Brain, brain aging, cognition, cognitive aging, crp, cytokines, diffusion mri, Healthy Minds for Life, inflammation, neuroscience, NODDI, vascular risk, white matterInflammation Tracks White-Matter MRI in Aging Adults
Chronic low-grade inflammation rises with age, and a growing body of work…
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anhedonia, Black Americans, CBT for psychosis, defeatist beliefs, mediation analysis, microaggressions, negative symptoms, PANSS, Psychiatry, Psychology, psychosis, racial discrimination, racial stress, schizophrenia, therapyBlack Americans Diagnosed with Schizophrenia 2.42x the Rate of White Americans: More Negative Symptoms
Black Americans are diagnosed with schizophrenia-spectrum disorders at 2.42 times the rate…
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agitation, antipsychotics, atypical antipsychotics, cardiovascular disease, CPRD, Dementia, Drugs, FDA black-box warning, matched cohort study, Neurodegenerative Diseases, older adults, Psychiatry, risperidone, side effects, strokeRisperidone Stroke Risk in Dementia: HR 1.28 Across CVD Subgroups
The risperidone-stroke link in dementia is one of the longest-running safety signals…
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anticoagulants, antidepressants, Anxiety, atrial fibrillation, bleeding, case-crossover, cohort study, depression, DOACs, drug interactions, Drugs, gastrointestinal bleeding, Interactions, intracranial hemorrhage, ssrisSSRIs + DOACs: No Excess Bleeding vs. Other Antidepressants
SSRIs raise bleeding risk on their own. DOACs (direct oral anticoagulants —…
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bipolar disorder, cardiac malformations, cohort study, Drugs, Ebstein anomaly, lithium, mood stabilizers, NICE guidelines, perinatal, postpartum psychosis, postpartum relapse, pregnancy, PsychiatryLithium in Pregnancy: Why Late Discontinuation Backfires
Lithium prescribing during pregnancy sits in a knot of competing risks. The…
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Autism, Danish registers, familial confounding, genetics, indirect genetic effects, iPSYCH, maternal health, Mendelian randomization, pregnancy, Psychiatry, sibling comparison, ssris, valproateMaternal Health and Autism Risk: Most Links Are Genetic, Not Prenatal
For two decades, headlines have linked autism to maternal obesity, depression, anxiety,…
