Neurodegenerative Diseases
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Brain, brain atrophy, bvFTD, cognition, diagnostic conversion, frontoinsular cortex, frontotemporal dementia, mri, Neurodegenerative Diseases, orbitofrontal cortex, Psychiatry, visual rating scalebvFTD MRI Atrophy Ratings: Left Orbitofrontal Score Predicted 3.77x Odds
A 2026 behavioral-variant frontotemporal dementia MRI study found that simple visual ratings…
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3D FLAIR MRI, Alzheimer’s disease, Brain, brain aging, brain lymphatics, cerebrospinal fluid, cervical lymph nodes, cognition, glymphatic system, meningeal lymphatic vessels, Neurodegenerative Diseases, neuroimaging, neuroscience, parkinson’s diseaseBrain Lymphatic MRI Shows Aging-Linked Drainage Changes
A 2022 Nature Communications study used non-contrast 3D T2-FLAIR magnetic resonance imaging…
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alpha-synuclein, Brain, dopaminergic neurons, IL-6, mouse model, MPTP, Neurodegenerative Diseases, neuroinflammation, neuroscience, parkinson’s disease, sex differencesIL-6 Deficiency Worsened Parkinson’s Mouse Models, Especially in Females
A 2026 mouse study found that complete IL-6 deficiency worsened motor dysfunction…
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autophagy, genetics, lysosomes, mitochondria, mitophagy, Neurodegenerative Diseases, neuroscience, Parkin, parkinson’s disease, PINK1, ubiquitinPINK1 and Parkin Link Parkinson’s Disease to Failed Mitochondrial Cleanup
A 2026 review ties the Parkinson’s disease genes PINK1 and parkin to…
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anti-CD20 therapy, Brain, cladribine, Delphi consensus, disease modifying therapy, high efficacy DMTs, multiple sclerosis, Neurodegenerative Diseases, neurology, neuroscience, patient involvement, personalized therapy, treatment adherenceMultiple Sclerosis Personalized Therapy: 70% Delphi Consensus
An Italian multiple sclerosis Delphi panel reached consensus on 116 of 166…
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alpha-synuclein, Alzheimer’s disease, blood brain barrier, Brain, microplastics, Neurodegenerative Diseases, neuroinflammation, neuroscience, oxidative stress, parkinson’s diseaseMicroplastics and Parkinson’s Disease: 6 Plausible Brain-Risk Pathways
A 2026 mechanistic review linked microplastics to 6 proposed Alzheimer’s disease pathways…
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Alzheimer’s disease, amyloid beta, blood brain barrier, Brain, cerebral blood flow, dementia biomarkers, Neurodegenerative Diseases, neuroscience, neurovascular unit, pericytesAlzheimer’s Neurovascular Unit Dysfunction May Start Before Amyloid
A 2026 review argues that neurovascular-unit dysfunction may precede amyloid-beta generation in…
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autophagy, genetics, lysosomes, neurodegeneration, Neurodegenerative Diseases, neuroscience, parkinson’s disease, potassium channel, proton channel, TMEM175TMEM175 Proton Channel Finding Clarifies Parkinson’s Lysosome Risk
A 2026 PNAS study found that TMEM175 behaves as a pH-sensitive lysosomal…
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action units, Brain, cognition, dementia screening, digital biomarkers, facial expression, mild cognitive impairment, MoCA, Neurodegenerative Diseases, neuroscience, older adults, OpenFaceFacial Markers Differed in 31 Older Adults With MCI-Level MoCA Scores
A 2026 medRxiv preprint found that older adults with mild-cognitive-impairment-level MoCA-J scores…
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autonomic dysfunction, Brain, brain-heart coupling, cognitive screening, ECG, eeg, freezing of gait, heart rate variability, MMSE, Neurodegenerative Diseases, neuroscience, parkinson’s diseaseParkinson’s Brain-Heart Coupling Signals MMSE and Freezing of Gait
A 2026 EEG-ECG preprint reported that beta efficiency-sympathetic coupling differed across healthy…
