GLOOM
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ACEs, adverse childhood experiences, Anxiety, AUC, Canada, childhood trauma, depression, early-life adversity, predictive accuracy, Psychiatry, Psychology, screening, Stress, substance use disorder, suicidalityACEs Poorly Predict Mental Illness in Canadian Data
A 2026 nationally-representative study by Johnson, Parker, and Wade in the Canadian…
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AI suicide risk, ChatGPT Health, clinical AI, crisis detection, mental health chatbots, Psychiatry, Psychology, safety agent, suicide, suicide-prevention, synthetic vignettesAI Suicide-Risk Agent Detected 91.5% vs. ChatGPT Health
A 2026 preprint found that an independent supervisory safety agent detected suicide-risk…
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addiction, behavioral addiction, childhood trauma, compulsive sexual behavior, gender differences, non-suicidal self-injury, problematic sexual behavior, Psychiatry, Psychology, self-harmWomen With Problematic Sexual Behavior Had Higher NSSI Risk
A 2026 preprint combining 2,189 university participants with 477 clinical patients with…
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alpha-synuclein co-pathology, alpha-synuclein SAA, ALZAN cohort, Alzheimer’s disease, Brain, CSF biomarkers, lewy body dementia, memory clinic biomarkers, Neurodegenerative Diseases, neuroscience, RT-QuICAlpha-Synuclein SAA Detected 95% of Lewy Body Dementia in ALZAN
A 2026 ALZAN memory-clinic cohort found that cerebrospinal-fluid alpha-synuclein seed amplification assay…
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cognition, cognitive remediation, Corsi block-tapping, dlpfc, Forward Digit Span, Neurostimulation, non invasive brain stimulation, Psychiatry, schizophrenia, sham-controlled trial, tdcs, transcranial direct current stimulation, working memorySingle-Session tDCS Fails Working-Memory Test in Schizophrenia
Transcranial direct current stimulation (tDCS) has been pitched as a scalable cognitive-enhancement…
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complement C4, crispr, CYFIP1, genetics, gwas, IRF8, ITGB2, microglia, MSR1, neuroscience, Psychiatry, schizophrenia, SYK, synaptic pruning, TREM2Schizophrenia Risk Genes Reshape Microglial Pruning in CRISPR Screen
Schizophrenia’s genetic architecture sits awkwardly between neurons and the immune system. A…
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ALS anxiety, amyotrophic lateral sclerosis, Anxiety, Beck Depression Inventory, depression, frontotemporal dementia, motor neuron disease, Neurodegenerative Diseases, Psychiatry, psychological distress, STAI, state anxiety, trait anxietyALS Anxiety: 18% State, 14% Trait in 433 Patients
In 433 non-demented amyotrophic lateral sclerosis (ALS) patients, clinically significant anxiety was…
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Anxiety, APRIL, biomarkers, Cancer Disparities Research Network, chronic inflammation, gp130, health disparities, IL-6, mind-body, MMP-1, Psychiatry, Psychology, Stress, underserved populationsAnxiety Biomarkers: gp130, MMP-1, APRIL in 190 Adults
The link between psychological stress and chronic inflammation is well-documented — what’s…
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depression, HDRS, heat-shock proteins, IL-6, inflammation, major depressive disorder, Natural Cures, neuroscience, Psychiatry, RNA-seq, whole-body hyperthermiaWhole-Body Hyperthermia for Depression: IL-6 Heat Genes
Whole-body hyperthermia looks less like generic relaxation and more like a timed…
