GLOOM
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clinical guidelines, Drugs, evidence synthesis, Hormones, iron deficiency, obstetric care, perinatal depression, pregnancy, restless legs syndrome, sleep, sleep disorders, stepped care, Willis-Ekbom diseaseRestless Legs in Pregnancy: Stepped-Care Recommendations
Restless legs syndrome (RLS), now also called Willis-Ekbom disease (WED), is a…
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depression symptoms, parent report, Psychiatry, Psychology, psychometrics, quality of life, screening, suicidality, youth mental healthParent Youth Quality-of-Life Scale Linked to Suicidality at r = -0.50
A 2,251-child national parent-report preprint found that the 7-item Parent-report Nationwide Quality…
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adolescent trauma, Brain, developmental trauma, fear extinction, fMRI, neuroscience, parent child synchrony, prefrontal cortex, PTSD, PTSD symptoms, safety learning, skin conductance, vicarious extinctionTrauma Disrupts Parent-Child Fear Extinction in Youth With PTSD Symptoms
A 97-dyad adolescent fMRI study found that trauma-exposed youth with high posttraumatic…
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Anxiety, AUROC, Brain, calibration, ENIGMA-OCD, neuroimaging biomarkers, neuroscience, OCD clinical AI, Psychiatry, resting-state fMRI, site generalization, transformer modelOCD Clinical AI Reached AUROC 0.653 but Failed Site Generalization
A 2026 ENIGMA-OCD preprint tested a transformer model on resting-state fMRI from…
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Anxiety, anxiety symptoms, CBT app, depression, depression symptoms, digital mental health, executive function training, Psychology, randomized controlled trial, therapy, workplace wellbeingWorkplace Mental Health Apps Split Outcomes: Anxiety Down, Wellbeing Up
A 228-person randomized trial found a split result for workplace mental-health apps:…
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aggression, antipsychotics, bdnf, cognition, inflammation, left DLPFC, Neurostimulation, randomized trial, risperidone, rtms, schizophreniarTMS Plus Risperidone Improved Schizophrenia Cognition
A 2026 randomized study involving 80 people with schizophrenia found that adding…
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caffeine, circadian rhythm, dopamine, Drosophila, Drugs, impulsivity, inhibitory control, motor behavior, mushroom body, neuroscience, nighttime caffeine, shift work, sleepNighttime Caffeine Increased Impulsivity Through Dopamine in Fly Study
A 2025 iScience study found that nighttime caffeine increased motor impulsivity in…
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behavioral activation, cognitive behavioral therapy, depression, depression remission, exercise priming, major depressive disorder, pilot randomized trial, Psychology, therapeutic alliance, therapyExercise Before CBT Raised Depression Remission to 69% in Pilot Trial
A 40-person pilot trial found depression remission in 69% of adults who…
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cognitive impairment, depression, depression genetics, endothelial dysfunction, first-episode depression, genetics, geriatric depression, inflammatory markers, MMSE, neuroscience, nitric oxide synthase, NOS3, Psychiatry, rs1799983NOS3 TT Variant Linked to 1.72x Cognitive Risk in First-Episode Depression
A 2026 cross-sectional study of 519 older adults with first-episode depression found…
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anti-CD20 therapy, Brain, cladribine, Delphi consensus, disease modifying therapy, high efficacy DMTs, multiple sclerosis, Neurodegenerative Diseases, neurology, neuroscience, patient involvement, personalized therapy, treatment adherenceMultiple Sclerosis Personalized Therapy: 70% Delphi Consensus
An Italian multiple sclerosis Delphi panel reached consensus on 116 of 166…
