Drugs
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AIP4, Alzheimer’s disease, amyloid beta, APP PS1 mice, Brain, cell cycle re-entry, clomipramine, drug repurposing, Drugs, Itch, memory, Neurodegenerative Diseases, neuronal apoptosisClomipramine Improved Alzheimer’s Mouse Memory by Blocking Itch in 45 Days
A 2026 iScience study found that 45 days of clomipramine improved spatial,…
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adenosine, black tea, caffeine, caffeine timing, coffee, Drugs, PSQI, Psychiatry, Psychology, sleep, sleep disturbances, sleep duration, sleep quality, working adultsCaffeine Intake and Sleep Quality: 428 Working Adults, Source by Source
A 2026 cross-sectional study involving 428 employed adults found that poor sleepers…
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anti-obesity medication, Diet & Nutrition, Drugs, effort moralization, GLP-1, medication stigma, moral judgment, obesity stigma, Ozempic, Psychology, semaglutide, social psychology, Wegovy, weight stigma, Weight-loss drugsGLP-1 Weight-Loss Drugs Triggered Effort-Based Stigma in 4 Studies
A 2026 Scientific Reports paper involving 1,205 participants found that people using…
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AD/ADRD, Alzheimer’s disease, APOE-e4, Brain, cardiovascular risk, cognitive decline, Dementia, Drugs, Kaiser Permanente, LDL cholesterol, Neurodegenerative Diseases, observational bias, statins, target trial emulationStatins and Dementia Risk: No Long-Term Signal in 322,358 Patients
Statins do not look like a dementia-prevention drug, but they do not…
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Immunotherapy could be used to treat depression, early trial suggests
Immunotherapy could be used to treat depression among patients who have not…
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ADNI, Alzheimer’s disease, amyloid, APOE, APOE-e4, blood biomarker, Brain, cognition, donanemab, Drugs, genetics, lecanemab, longitudinal cohort, mild cognitive impairment, Neurodegenerative Diseases, neuroscience, p-tau217, preclinical ADPlasma p-tau217 Blood Test Predicts Alzheimer’s Risk 1.5x Stronger in APOE-e4
Until recently, Alzheimer’s pathology could only be confirmed in living patients via…
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5-HT7, acute psychosis, antipsychotics, d2 receptor, Drugs, JEWEL trial, lurasidone, negative symptoms, Neurotransmitters, PANSS, positive symptoms, Psychiatry, psychosis, schizophreniaLurasidone Improves Positive Symptoms of Schizophrenia More Than Negative
Lurasidone is approved for schizophrenia and bipolar depression on the strength of…
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agitation, antipsychotics, atypical antipsychotics, cardiovascular disease, CPRD, Dementia, Drugs, FDA black-box warning, matched cohort study, Neurodegenerative Diseases, older adults, Psychiatry, risperidone, side effects, strokeRisperidone Stroke Risk in Dementia: HR 1.28 Across CVD Subgroups
The risperidone-stroke link in dementia is one of the longest-running safety signals…
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anticoagulants, antidepressants, Anxiety, atrial fibrillation, bleeding, case-crossover, cohort study, depression, DOACs, drug interactions, Drugs, gastrointestinal bleeding, Interactions, intracranial hemorrhage, ssrisSSRIs + DOACs: No Excess Bleeding vs. Other Antidepressants
SSRIs raise bleeding risk on their own. DOACs (direct oral anticoagulants —…
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bipolar disorder, cardiac malformations, cohort study, Drugs, Ebstein anomaly, lithium, mood stabilizers, NICE guidelines, perinatal, postpartum psychosis, postpartum relapse, pregnancy, PsychiatryLithium in Pregnancy: Why Late Discontinuation Backfires
Lithium prescribing during pregnancy sits in a knot of competing risks. The…
